James Cook could earn his best role of the season if the Bills pummel the Giants as expected on Sunday. Who else is worth a lineup spot for the tricky single-game slate?

Seattle's passing attack could be in for a big night against the Giants tonight. Which players should we target on Monday's single-game slate?

Monday Night Football is back with the Seattle Seahawks visiting the New York Giants. Can Kenneth Walker III exploit the Giants' defensive woes and lead the Seahawks to victory?

With Andy Dalton under center, Adam Thielen is a must-start in a revenge game against the Vikings. How else should you handle start/sit decisions in Week 4?

Daniel Jones will have his work cut out for him against a tough San Francisco defense, but his rushing upside puts him in the single-slate MVP conversation. Which other players should we consider in the multiplier slot?

Thursday Night Football is back for Week 3. Can the New York Giants handle Christian McCaffrey and the San Francisco 49ers?